Can D-Dimer detect blood clots caused by snake venom?

The study included 1363 patients who were quantitatively evaluated for D-dimer within 24 hours of suspected or confirmed snakebite.

Diagnostic performance of the D-Dimer . Test

D-dimer values ​​increased to 2.5 mg/L within three hours of the bite among 95% of patients who developed VICC and to less than 2.5 mg/L for 95% of patients not examined within six hours after being bitten by a snake.


Diagnostic performance improved in the first three hours after a snake bite; for quantitative D-dimer testing at 2-6 hours.

In one of the 84 patients who developed VICC-associated acute kidney injury, D-dimer values ​​exceeded 4 mg/L within 24 hours of the bite.

The study concluded that the estimated D-dimer concentration 2-6 hours after a snake bite, with a cut-off value of 2.5 mg/L, could serve as an important diagnostic tool for detecting VICC.

Source: Medindia

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