Although the presentation has some overlap with adults, children still have differences. The risk for PASC appears to be higher in children younger than 5 years of age, those with complicated medical conditions, and those admitted to the intensive care unit with their initial COVID-19 infection.
The researchers used electronic health record data from PEDSnet member organizations of 659,286 children tested for SARS-CoV-2 and compared 59,893 children who tested positive with those who tested positive. have negative test results.
A multi-level analysis was then conducted using EHR data of children and persons under 21 years of age who underwent testing for SARS-CoV-2 in one of eight pediatric health systems in the country from day 1. March 2020 to October 31, 2021. .
Clinicians identified conditions, symptoms, and medications associated with PASC within one to six months of the trial. Of the 660,000 children tested, 9% were positive and most tested were outpatients.
Symptoms most strongly associated with infection include changes in the sense of smell and taste, hair loss, chest pain, abnormal liver enzymes, skin rash, fever and chills, fatigue and malaise.
The conditions most associated with infection include myocarditis, acute respiratory failure, and myositis. There was also a higher association with mental health treatment among children with positive PASC test results compared with children with negative test results.